The Chemistry of Ynamides: Development, Syntheses, and Applications in Organic Synthesis (Original PDF from Publisher)

The Chemistry of Ynamides Development

In ynamides, a nitrogen atom with an electron-withdrawing group is directly joined to a triple bond. Their highly polarized triple bond, which permits the creation of distinctive chemical reactions, makes them an exceptionally valuable and new class of reagents. Despite being found by Viehe in 1972, little is known about their chemistry, and the resurgence of ynamide chemistry began at the turn of the 20th century when effective synthesis techniques were developed.Since then, ynamide chemistry has advanced at an exceptionally rapid pace, particularly during the last two decades. Although there are a number of reviews on ynamide chemistry, the majority of them are outdated or only cover specific facets of the subject, and there is currently no book on the subject. A thorough book on ynamide chemistry is so much needed and would be timely.

All facets of ynamide chemistry are covered in this book, including their discovery, synthesis, use as coupling reagents, and applications in heterocyclic chemistry, natural product synthesis, and organometallic chemistry. For researchers working in the field, readers interested in synthesis in general, and those wishing to enter the field and require a thorough and current review, it offers a methodical and thorough understanding of ynamide chemistry. In order to further promote the advancement of ynamide chemistry, this book will surely be crucial in bridging the past and the future.